The importance of lattice QCD to our understanding of the structure, 
spectroscopy and interactions of hadrons has been demonstrated in 
several salient publications by the QCDSF Collaboration. Our primary 
goal is to acquire a quantitative description of the physics of 
hadrons. The novel feature of this proposal is that the calculations 
will be done directly at the physical quark masses on lattices of up 
to 5 fm diameter. This will allow us to compute many hadronic 
observables with unambiguous precision, and address aspects of hadron 
physics not accessible by experiment. Several of these calculations 
will have direct impact on high-energy physics and on our 
understanding of the Standard Model of particle physics. For many 
hadronic observables it is fundamental to include strange sea quarks.